Strength of T cell signaling regulates HIV-1 replication and establishment of latency
by Matthew Gagne, Daniel Michaels, Gillian M. Schiralli Lester, Suryaram Gummuluru, Wilson W. Wong, Andrew J. Henderson
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by Matthew Gagne, Daniel Michaels, Gillian M. Schiralli Lester, Suryaram Gummuluru, Wilson W. Wong, Andrew J. Henderson
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by Maysa Pellizzaro, Camila Marinelli Martins, Ana Carolina Yamakawa, Diogo da Cunha Ferraz, Vivien Midori Morikawa, Fernando Ferreira, Andrea Pires dos Santos, Alexander Welker Biondo, Helio Langoni
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by Prasanna Santhanam, Steven P. Rowe, Jenny Pena Dias, Rexford S. Ahima
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by Brittany I. Davidson, Simon L. Jones, Adam N. Joinson, Joanne Hinds
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by Sucheta Sehgal, Nitish D. Patel, Avinash Malik, Partha S. Roop, Mark L. Trew
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by Tom Brough, William Rayment, Steve Dawson
Quantifying the distribution of prey greatly improves models of habitat use by marine predators and can assist in determining threats to both predators and prey. Small epipelagic fishes are important prey for many predators yet their distribution is difficult to quantify due to extreme patchiness. This study explores the use of recreational grade echosounders (RGE) to quantify school characteristics of epipelagic fish and link their distribution to that of their predators at Banks Peninsula... Читать дальше...
by Jingping Zuo, Jianhua Xu, Weihong Li, Dongyang Yang
Quantitatively evaluating the spatiotemporal variation of soil moisture (SM) and its causes can help us to understand regional eco-hydrological processes. However, the complicated geographical environment and the scarce observation data make it difficult to evaluate SM in Northwest China. Selecting the Tarim River Basin (TRB) as a typical representative of the data-scarce area in Northwest China, we conducted an integrated approach to... Читать дальше...
by Zamzam Ahmed, Mohammad Saada, Alan M. Jones, Abdullah M. Al-Hamid
Medical errors are of economic importance and can contribute to serious adverse events for patients. Medical errors refer to preventable events resulting from healthcare interactions, whether these events harm the patient or not. In Kuwait, there is a paucity literature detailing the causes, forms, and risks of medical errors in their state-funded healthcare facilities. This study aimed to explore medical errors, their causes... Читать дальше...
by Jessica M. Kendall-Bar, Alexei L. Vyssotski, Lev M. Mukhametov, Jerome M. Siegel, Oleg I. Lyamin
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by Isadora Prado Cano, Thiago José Dionisio, Tânia Mary Cestari, Adriana Maria Calvo, Bella Luna Colombini-Ishikiriama, Flávio Augusto Cardoso Faria, Walter Luiz Siqueira, Carlos Ferreira Santos
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by Farial Tavakoli, Mohamad Reza Ganjalikhany
EGFR (epidermal growth factor receptor) plays the critical roles in the vital cell activities, proliferation, differentiation, migration and survival in response to polypeptide growth factor ligands. Aberrant activation of this receptor has been demonstrated in many human cancers, particularly in non-small cell lung carcinoma (NSCLC). L858R point mutation is the most common oncogenic mutation in EGFR tyrosine kinase domain in patients with EGFR-mutated NSCLC. Читать дальше...
by Alexander P. Landry, Zsolt Zador, Rashida Haq, Michael D. Cusimano
BackgroundThe subtyping of breast cancer based on features of tumour biology such as hormonal receptor and HER2 status has led to increasingly patient-specific treatment and thus improved outcomes. However, such subgroups may not be sufficiently informed to best predict outcome and/or treatment response. The incorporation of multi-modal data may identify unexpected and actionable subgroups to enhance disease understanding and improve outcomes. Читать дальше...
by Gandura Omar Abagandura, Songul Şentürklü, Navdeep Singh, Sandeep Kumar, Douglas G. Landblom, Kris Ringwall
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by Muhammad Ashfaq, Gergin Blagoev, Hafiz Muhammad Tahir, Arif M. Khan, Muhammad Khalid Mukhtar, Saleem Akhtar, Abida Butt, Shahid Mansoor, Paul D. N. Hebert
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by Joel D. Rindelaub, Zane Baird, Bruce A. Lindner, Angela A. Strantz
With the ability to create customizable products tailored to individual patients, the use of 3D printed medical devices has rapidly increased in recent years. Despite such interest in these materials, a risk assessment based on the material characterization of final device extracts—as per regulatory guidance—has not yet been completed, even though the printing process may potentially impact the leachability of polymer components. Читать дальше...
by Leo C. McHugh, Kevin Snyder, Thomas D. Yager
BackgroundThe performance of a new diagnostic test is typically evaluated against a comparator which is assumed to correspond closely to some true state of interest. Judgments about the new test’s performance are based on the differences between the outputs of the test and comparator. It is commonly assumed that a small amount of uncertainty in the comparator’s classifications will negligibly affect the measured performance of a diagnostic test. Читать дальше...
by Hui-Lin Lin, Chih-Hsin Muo, Cheng-Yu Lin, Hsuan-Ju Chen, Pei-Chun Chen
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by Peter D. Soyster, Aaron J. Fisher
Ecological momentary assessment (EMA) is a data collection method that involves repeated sampling of participants’ real-time experience and behavior as they unfold in context. A primary challenge in EMA research is to design surveys that adequately assess constructs of interest while minimizing participant burden. To achieve this balance, researchers must make decisions regarding which constructs should be included and how those constructs should be assessed. Читать дальше...
by Elvira Jimenez Vera, Yi Vee Chew, Leigh Nicholson, Heather Burns, Patricia Anderson, Hsiao-Ting Chen, Lindy Williams, Karen Keung, Negar Talaei Zanjani, Suat Dervish, Ellis Patrick, Xin Maggie Wang, Shounan Yi, Wayne Hawthorne, Stephen Alexander, Philip J. O’Connell, Min Hu
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by Negeso Gebeyehu Gejo, Abebe Alemu Anshebo, Leta Hinkosa Dinsa
BackgroundPostpartum family planning is the initiation and use of family planning services within the first 12 months following childbirth to impede closely spaced and unintended pregnancies. Globally, spacing pregnancies at least 2 years apart can prevent an estimated 10% of infant deaths and 21% of deaths in children 1–4 years of age. The main purpose of this study was to determine postpartum modern contraceptive use and associated factors in Hossana town... Читать дальше...
by Jungyeon Kim, Kum-Boo Choi, Ju Hun Park, Kyoung Heon Kim
Fermented vegetables have emerged as prebiotics with various health benefits. However, the possible mechanisms behind their health benefits are unclear. To relate the metabolite profile changes in fermented mixed vegetables with associated health benefits of fermented vegetables, we analyzed the metabolite profiles of mixed vegetables, before and after fermentation by Lactobacillus plantarum, using gas chromatography/time-of-flight–mass spectrometry (GC/TOF–MS). Читать дальше...
by Chun-Cheng Wang, Ming-Yi Shen, Kuan-Cheng Chang, Guei-Jane Wang, Shu-Hui Liu, Chiz-Tzung Chang
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by Yongchun Shi, Hui Sun, Xiaoran Wang, Weihuan Jin, Qianyi Chen, Zhengdong Yuan, Haidong Yu
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by Habtamu Ayalew, Pak Wah Tsang, Chenggen Chu, Junzhou Wang, Shuyu Liu, Caifu Chen, Xue-Feng Ma
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by Hannah A. Edwards, Julia Schroeder, Hannah L. Dugdale
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