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Новости за 22.11.2022

Birth choices after previous cesarean and risk of pelvic floor surgery

Sciencedaily.com 

Vaginal birth after a previous cesarean section is associated with an increased risk of pelvic floor surgery compared with planning another cesarean, according to a new study. The findings provide useful information to help women who have had a previous cesarean section when planning how to give birth in their next pregnancy.

Challenging guidelines on pregnancy interval following miscarriage or abortion

Sciencedaily.com 

Conception within three months of a miscarriage or an abortion is not associated with increased risks of adverse pregnancy outcomes, according to new research. The study suggests that, contrary to current advice, women could attempt pregnancy after a previous miscarriage or induced abortion without elevated perinatal risks and reassures those who want to try again sooner than guidelines recommend.

Of mice and men: Treating acne with systemic antibiotics can have unintended consequences on the maturing skeleton during adolescence

Sciencedaily.com 

Adolescence is a time of significant skeletal development. In a new report, researchers showed that long-term use of minocycline, an antibiotic used for the systemic treatment of adolescent acne, disrupts the normal gut microbiome, leading to poor bone maturation. Surprisingly, these effects were caused by a change in the gut microbiome, leading to an altered profile of bile acids -- molecules that aid digestion and communicate with many organs -- that suppressed the activity of bone-forming cells called osteoblasts... Читать дальше...



New insight into how long-banned chemicals (PCBs) unleash their toxicity inside the body

Sciencedaily.com 

In the past, PCBs were utilized in a vast range of industrial and commercial products. These highly carcinogenic chemical compounds remain in our environment and accumulate inside organisms. Chiral PCBs are particularly dangerous because they have more chlorine atoms, which are hard for the body to break down, so they can accumulate in the body easily. Also, their isomers are metabolized differently, causing isomer-specific toxicity (particularly neurodevelopmental issues). Scientists reveal exactly... Читать дальше...

Cultural differences affect how we support close friends and family

Sciencedaily.com 

A new study found that differences in culture affect when Japanese and American university students feel comfortable providing social support. The researchers found that Japanese university students were less likely than American students to offer assistance to a close friend or family member unless they had been explicitly asked for help, even when they knew that the person needed assistance. There were no differences in providing assistance between Japanese and American students when requests for help were explicitly stated.



Great potential for aquifer thermal energy storage systems

Sciencedaily.com 

Aquifer thermal energy storage systems can largely contribute to climate-friendly heating and cooling of buildings: Heated water is stored in the underground and pumped up, if needed. Researchers have now found that low-temperature aquifer thermal energy storage is of great potential in Germany. This potential is expected to grow in future due to climate change.

Breaking nitrogen while generating methane

Sciencedaily.com 

Scientists have successfully enhanced cultivation of a microorganism that can fix nitrogen (N2) while producing methane (CH4) and ammonia (NH3) and investigated exciting details of its metabolism.

Development of the next generation of microscopes

Sciencedaily.com 

A completely new type of microscope can take 3D images of cells -- while working in a natural environment. The new technology is significantly faster and better than before and will give researchers new opportunities.

New way to synthesize mRNAs enhancing effectiveness of mRNA drugs and vaccines

Sciencedaily.com 

A team of synthetic biologists has recently discovered a way that could increase synthetic mRNA's protein production efficiency by up to 10 times, which means the effectiveness of mRNA vaccines and drugs -- such as those used against cancer, COVID-19 or other genetic diseases, will be greatly boosted with even less dosage of the mRNAs.

Sequencing project to unleash the biotechnology potential of euglenoids

Sciencedaily.com 

An ambitious plan to sequence the genomes of all known species of euglenoids over the next decade has been launched. The network of scientists behind the initiative believe it has the potential to drive breakthroughs ranging from new biofuels and sustainable foods to cancer medicines.

Unexpected cognitive deteriorations in epilepsy

Sciencedaily.com 

In severe epilepsies, surgical intervention is often the only remedy -- usually with great success. While neuropsychological performance can recover in the long term after successful surgery, on rare occasions, unexpected declines in cognitive performance occur. Researchers have now been able to show which patients are at particularly high risk for this.

Silicone sponge captures unknown bacteria

Sciencedaily.com 

From human intestines to the bottom of the sea: Microorganisms populate nearly any habitat, no matter how hostile it is. Their great variety of survival strategies is of huge potential in biotechnology. Most of these organisms, however, are unknown, because they cannot be cultivated. To make better use of this 'microbial dark matter', a team of researchers has now developed a 'sponge' made of porous, formable silicone. Embedded in a chip, the material sucks up microorganisms in the surroundings, which can then be applied for further research.

Discovery suggests new way to target mantle cell lymphoma

Sciencedaily.com 

A form of blood cancer known as mantle cell lymphoma is critically dependent on a protein that coordinates gene expression, such that blocking its activity with an experimental drug dramatically slows the growth of this lymphoma in preclinical tests.


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HIV infection leaves a 'memory' in cells

Sciencedaily.com 

Though antiretroviral therapy has made HIV a manageable disease, people living with HIV often suffer from chronic inflammation. This can put them at an increased risk of developing comorbidities such as cardiovascular disease and neurocognitive dysfunction, impacting the longevity and quality of their lives. Now, a new study explains why chronic inflammation may be happening and how suppression or even eradication of HIV in the body may not resolve it.

Remdesivir reduces COVID-19 mortality in a real-world setting

Sciencedaily.com 

Researchers have found that administering remdesivir with corticosteroids to Asian patients who are critically ill with COVID-19 within 9 days of symptom onset reduces overall mortality. Starting treatment later did not have the same effect, suggesting that higher viral loads and serious lung damage impair the effectiveness of this treatment.

Limiting global warming now can preserve valuable freshwater resource

Sciencedaily.com 

A research team has found that the Andean region of Chile could face noticeable snow loss and roughly 10% less mountain water runoff with a global warming of approximately 2.5 degrees Celsius compared to pre-industrial levels over the next three decades. The study also shows that what happens in the Andes could be a harbinger of what is to come for the California Sierra Nevada mountain range, and highlights the importance of carbon-mitigation strategies to prevent this from occurring.

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