World's first stem cell treatment for spina bifida delivered during fetal surgery
Three babies have been born after receiving the world's first spina bifida treatment combining surgery with stem cells.
Three babies have been born after receiving the world's first spina bifida treatment combining surgery with stem cells.
Scientists have long looked to the brain as an inspiration for designing computing systems. Some researchers have recently gone even further by making computer hardware with a brainlike structure. These 'neuromorphic chips' have already shown great promise, but they have used conventional digital electronics, limiting their complexity and speed.
The key to a new cardiomyocyte-making technique is a gene activity-controlling protein called Ascl1, which is known to be a crucial protein involved in turning fibroblasts into neurons. Researchers had thought Ascl1 was neuron-specific.
Growing nutritious, protein-dense microalgae in onshore, seawater-fed aquaculture systems -- particularly along the coasts of the Global South -- could help increase food production by more than 50% and feed a projected 10 billion people by 2050.
In a new review article, biology researchers make the case for reevaluating maligned non-native species to consider benefits as well as costs.
The drug tofacitinib was well tolerated among patients with early scleroderma, primarily affecting the protein interferon both in fibroblasts and keratinocytes. Researchers say the drug is safe and can possibly be repurposed for systemic sclerosis treatment.
Synthetic fuels produced from renewable sources, so-called refuels, are deemed potential game changers in fighting climate change. Refuels promise to reduce CO2 emissions by up to 90% compared to conventional fuels and they allow for the continued use of existing vehicle fleets with combustion engines and of the refueling infrastructure, from fuel production to transport to sales. Researchers carried out extensive fleet tests in a large-scale project with industry partners and proved that refuels... Читать дальше...
Researchers have developed an imaging agent for demyelination and evaluated its use in healthy human volunteers.
Scientists have made a significant genetic discovery that sheds light on the use of the drug caspofungin to treat a deadly fungal infection, Aspergillus fumigatus, which kills some 100,000 severely immunocompromised people each year.
This year, about 200,000 people will be diagnosed with non-small-cell lung cancer, the second leading cause of death after cardiovascular disease. Researchers are working to improve the odds for these patients in two recently published studies that combine novel multiplex cellular imaging methods with artificial intelligence to learn why and how patients respond differently to disease and treatments.
Using chemical design and synthesis, scientists brought together the Nobel-prize winning technology with therapeutic technology to overcome a critical limitation of CRISPR. Specifically, the groundbreaking work provides a system to deliver the cargo required for generating the gene editing machine known as CRISPR-Cas9.
Using a new power sector model, a team of researchers has proposed a method for Europe to eliminate natural gas imports from Russia.
Researchers have identified the gene TDRD7 as a key regulator against influenza A virus (IAV), which causes respiratory tract infections in 5 to 20 percent of the human population.
Algorithms can predict the in-game actions of volleyball players with more than 80% accuracy, and now the lab is collaborating with the Big Red hockey team to expand the research project's applications.
A new study identifies the political factors that allow some countries to lead in adopting cleaner sources of energy while others lag behind. By analyzing how different countries responded to the current energy crisis and to the oil crisis of the 1970s, the study reveals how the structure of political institutions can help or hinder the shift to clean energy. The findings offer important lessons as governments race to limit the impacts of climate change.
A discovery about how some visually impaired adults could start to see offers a new vision of the brain's possibilities. The adult brain has the potential to partially recover from inherited blindness, according to new research.
Researchers have developed a low-cost imaging system that can provide quantitative information about how deep within tissue a cancer cell resides. The system can help surgeons distinguish healthy tissue from tumors and could minimize health disparities in low-resource clinical centers.
Targeting a condition suffered by nearly a billion people worldwide, a new study has shown a drug previously used to treat depression can reduce obstructive sleep apnea (OSA) severity. While not yet identifying a cure, the authors say the study opens up further avenues for the development of future drug treatments targeted at the huge number of people unable to tolerate current sleep apnea therapies, such as continuous positive airway pressure (CPAP) machines.
A research team succeeds in developing anode-free Li batteries with maximized energy density, improving energy density by 40%.
Researchers have revealed that common liver diseases are not driven by inflammatory cell death as previously thought, resolving a long-standing controversy in gastroenterology and pointing to a new direction for treatment.
Entangled systems containing multiple quantum particles offer significant benefits in implementing quantum algorithms, which have the potential to be used in communications, data security or quantum computing. Researchers have been working to develop the first programmable optical quantum memory.
Two proteins ensure that cells can take up iron when needed. If both control proteins are switched off in mice, the animals develop severe anemia, as expected. Surprisingly, at the same time a cell type of the innate immune defense, the neutrophils, also dramatically decreases. Iron deficiency, a known defense mechanism against infectious pathogens, is a double edged sword, as it simultaneously curbs the defensive power of an important arm of the innate immune system.
Wear and tear in engines contributes to a lot of wasted fuel and can be dangerous for operators. Now, a collaborative group has created a way to computationally predict wear and tear in piston engines, allowing for enhanced safety measures in automobiles and industrial machinery.
Geneticists have discovered a previously unknown lineage of wild goats over ten millennia old. The new goat type, discovered from genetic screening of bone remains and referred to as 'the Taurasian tur', likely survived the Last Glacial Maximum (the ice age), which stranded their ancestors in the high peaks of the Taurus Mountains in Turkey where their remains were found.
New research has found some pelagic seabirds fly directly towards the eye of a storm, which researchers think may help them avoid being forced onto land masses, reducing the risk of injury or death.
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