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After more than a decade of research, scientists have discovered the natural mechanism behind a novel form of cell death called ferroptosis. The work, described in the current issue of Cell, points toward an entirely new strategy for treating many types of cancer and neurodegenerative diseases.

Despite some modest progress over the past two decades, Canada's waste diversion efforts remain wanting: according to the Canadian government, only 27% of the country's waste is recycled, composted, or otherwise diverted from disposal. In 2022, 26.6 million tons of solid waste wound up in landfills or was incinerated—an 11% increase from 2002.

Understanding how cells are organized and how their molecular components interact in a coordinated and cooperative manner is a central goal of modern life sciences. To answer these questions, researchers need to observe many structures inside the same cell at once and map how they are arranged and interact. This requires "multiplexed super-resolution microscopy"—an advanced imaging approach that reveals cellular details far beyond the limits of conventional light microscopes.

Recently-revealed notebooks belonging to a late paleontologist contain the missing information needed to help researchers finish their study of a remarkable fossil discovered nearly three decades ago.

A new catalyst strategy developed at Institute of Science Tokyo uses BaSi2 as a support for nickel and cobalt to decompose ammonia at lower temperatures. By forming unique ternary transition metal–nitrogen–barium intermediates that facilitate nitrogen coupling, the system lowers the energy barrier for ammonia decomposition. This enables nickel- and cobalt-based catalysts to achieve high hydrogen-production activity at reduced temperatures, matching the performance of ruthenium while relying on Earth-abundant... Читать дальше...

A research group led by Associate Professor Tetsuya Muramoto from the Faculty of Science, Toho University, has established a CRISPR genome editing technique that enables comparative analysis of the evolution of multicellularity across different species of social amoebae (cellular slime molds). Until now, genetic studies had largely been restricted to a single model species, limiting cross-species comparisons. The work is published in Scientific Reports.

Intrinsically disordered proteins lack a fixed structure, which is why they have been considered "undruggable" targets for drug development for years. However, these proteins play a key role in numerous diseases—ranging from various types of cancer to neurodegenerative disorders—long limiting the therapeutic options available to treat them.

The temperate rainforests of the Chilean Coast Range are home to a spectacular array of life: iridescent blue lizards, tiny wild cats called kodkods, and curly vines of waxy red bellflowers. Towering over this biodiversity are endangered ancient conifers, called alerce (Fitzroya cupressoides), whose trunks can get as wide as shipping containers. These alerce forests show exceptionally low mortality and grow slowly—one tree lived more than 3,600 years.

A University of Queensland study has shown that a deadly scorpion's venom carries an extra biochemical sting that could be used to guide future medical treatments and tests. The paper is published in the journal Biochimie.

Researchers at the University of Bath have developed a new technology that uses bacteria to build, chemically stabilize, and test millions of potential drug molecules inside living cells, making it much quicker and easier to discover new treatments for difficult-to-treat cancers.

Private companies are no longer peripheral participants in U.S. space activities. They provide key services, including launching and deploying satellites, transporting cargo and astronauts to the International Space Station, and even sending landers to the moon.

The Vera C. Rubin Observatory has started releasing its first discoveries: including supernovae, variable stars and asteroids, which will from now on be discovered at an astonishing rate as it begins its Legacy Survey of Space and Time, a ten-year survey probing the deepest reaches of the universe.

Indigenous people who were the first to inhabit the area now known as Michigan—before the Europeans arrived—may have cultivated maize (corn) more prominently than previously assumed for such a northern population. Researchers from the University of New Hampshire found that using modern global satellite data in a novel way helped them connect archaeological features—like ancient burial mounds—to environmental data of lake temperatures and gain new insights into past human–environment relationships.