3′UTR-derived small RNA couples acid resistance to metabolic reprogramming in Salmonella within macrophages

Acid resistance is a crucial property that enterobacteria must possess to withstand host acidic environments during infection, including the gastrointestinal tract and macrophage phagosomes. The facultative intracellular pathogen Salmonella expresses the arginine decarboxylase AdiA, which confers acid resistance by catalyzing an H+-consuming reaction.