by Elodie Gazanion, Laurent Lacroix, Patrizia Alberti, Pratima Gurung, Sharon Wein, Mingpan Cheng, Jean-Louis Mergny, Ana Rita Gomes, Jose-Juan Lopez-Rubio
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by Tom L. Kaufmann, Ulrich S. Schwarz
Recent experiments with super-resolution live cell microscopy revealed that nonmuscle myosin II minifilaments are much more dynamic than formerly appreciated, often showing plastic processes such as splitting, concatenation and stacking. Here we combine sequence information, electrostatics and elasticity theory to demonstrate that the parallel staggers at 14.3, 43.2 and 72 nm have a strong tendency to splay their heads away from the minifilament, thus... Читать дальше...
by Philippe Carmona, Sylvain Gandon
Many infectious diseases exhibit seasonal dynamics driven by periodic fluctuations of the environment. Predicting the risk of pathogen emergence at different points in time is key for the development of effective public health strategies. Here we study the impact of seasonality on the probability of emergence of directly transmitted pathogens under different epidemiological scenarios. We show that when the period of the fluctuation is large relative to the duration of the infection... Читать дальше...
by Elisa Benincà, Thomas Hagenaars, Gert Jan Boender, Jan van de Kassteele, Michiel van Boven
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by Madison S. Krieger, Carson E. Denison, Thayer L. Anderson, Martin A. Nowak, Alison L. Hill
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by Konstantin Butenko, Christian Bahls, Max Schröder, Rüdiger Köhling, Ursula van Rienen
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by Thuy T. T. Le, Frederick R. Adler
The benefits of mammography screening have been controversial, with conflicting findings from various studies. We hypothesize that unmeasured heterogeneity in tumor aggressiveness underlies these conflicting results. Based on published data from the Canadian National Breast Screening Study (CNBSS), we develop and parameterize an individual-based mechanistic model for breast cancer incidence and mortality that tracks five stages of breast cancer progression... Читать дальше...
| Tele1'den çağrı RTÜK’ün TELE1 TV ve Halk TV’ye verdiği 5 günlük ekran karartma cezasına tepkiler sürerken TELE1 Genel Yayın Yönetmeni Merdan Yanardağ, “Aydınlık için bir dakika karartma” çağrısı yaptı. |
Raheja QBE reported a net loss of Rs 62.1 crore for the year ended March 2020, compared with Rs 20.3 crore in the previous financial year.
MANY of you will have winced when Ole Gunnar Solskjaer compared Mason Greenwood favourably with a young Wayne Rooney. Here we go again, a talented English kid scores a couple of bangers and is over-hyped to the skies. Cool your boots, don’t over-burden him, you’ll build him up to knock him down and yada yada […]
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